منابع مشابه
Proteomic Identification of Monoclonal Antibodies from Serum
Characterizing the in vivo dynamics of the polyclonal antibody repertoire in serum, such as that which might arise in response to stimulation with an antigen, is difficult due to the presence of many highly similar immunoglobulin proteins, each specified by distinct B lymphocytes. These challenges have precluded the use of conventional mass spectrometry for antibody identification based on pept...
متن کاملSerum Antibodies Against Desipramine
I N RECENT YEARS more and more drugs have become implicated as causes of thrombocytopenia. In many instances correlations were made from clinical reports, and occasionally in vitro methods have demonstrated the presence of antibodies specific for a certain drug.1’2 In the present paper two cases were studied in which in vitro methods suggested that thrombocytopenia was induced by desipramine (P...
متن کاملProtective activity of the antilipopolysaccharide antibodies from human cord serum.
We evaluated the ability of human maternal and cord serum antibodies to protect mice challenged with live Escherichia coli serotype O6:K2ac (E. coli O6). Mice received paired maternal or cord serum pools before a challenge with E. coli O6 to evaluate the mortality rate. All the pools were able to protect the animals challenged with bacteria except the test group from paired maternal and cord se...
متن کاملSpecificity of human serum antibodies against endotoxin from N. gonorrhoeae.
Sera from patients with gonorrhoea were used to study the specificity of human antibodies against determinant a of endotoxin from gonococcal strains 8551, V, and VII. The sera were tested by an indirect haemagglutination technique before and after absorption with endotoxin from the same strains. The sera were used untreated and treated with mercaptoethanol (ME). The untreated and ME-treated ser...
متن کاملHuman serum antibodies reacting with endotoxin from Neisseria gonorrhoeae.
The chemical composition and serological properties of endotoxin prepared from gonococci by extraction with aqueous ether have been described in previous reports (Maeland, 1969b, 1969c). Aqueous ether endotoxin contains one antigenic determinant of carbohydrate nature (determinant a) and another antigenic determinant of protein nature (determinant b) (Maeland, 1968, 1969a). A serological test s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Methods
سال: 2012
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.2009